Have a history of kidney disease
They have had autoimmune diseases
Frequently use anti-inflammatory drugs (such as ibuprofen, naproxen, or diclofenac)
Suffering from obesity or metabolic syndrome
In these cases, protein loss can begin long before visible symptoms appear.
The relationship between high blood pressure and kidney damage
High blood pressure puts constant pressure on the kidneys. This elevated pressure affects the delicate renal filtration system day after day. Initially, the kidneys resist. Over time, this prolonged pressure deforms the internal filters, known as glomeruli.
When the glomerulus is damaged, it loses its ability to filter properly. It becomes more permeable and allows protein to leak out, which not only indicates damage but also accelerates its progression. This creates a vicious cycle: more damage, greater protein loss, and further kidney deterioration.
How to detect the problem early