• Painful red or purple skin plaques
• Tender bumps on the face, neck, or arms
• Fever or flu-like symptoms
• Fatigue or malaise
• Skin swelling or inflammation
The lesions are often highly sensitive to touch and may appear suddenly without warning.
Differential Diagnosis
Because several skin conditions can mimic its appearance, doctors must rule out other possible disorders before confirming the diagnosis.
Conditions considered during evaluation include:
• Urticaria (hives)
• Contact dermatitis
• Drug eruptions (toxicoderma)
• Cutaneous lupus
A skin biopsy combined with laboratory findings is typically required for a definitive diagnosis.
Treatment and Management
The first-line treatment for Sweet syndrome is systemic corticosteroid therapy.
Common treatments include:
Oral Corticosteroids